The interplay between ion channels and T cell immunology has emerged as a pivotal area in both basic and translational research. Ion channels, particularly voltage‐gated potassium channels such as Kv1 ...

The field of neurotrauma and epilepsy research has increasingly highlighted the pivotal influence of ion channels in the transition from traumatic brain ...

When a scrappy team of scientists joined forces in the late 1990s, they sought to identify genetic mutations that could have an outsized impact on the treatment of human disease. At the time, that ...

More is not necessarily better, as was previously examined in an article about the pitfalls of high-throughput screening (GEN, March 15, 2006, pg. 24), not the least of which is the terabytes of ...

Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, ...

Ion channels enable passive ion flow towards equilibrium, which is driven by ion concentration differences across the membrane and the membrane potential (the difference electric potential between the ...

Variants of the KCNC1 gene impact K v 3.1 potassium channel function, resulting in neurodevelopmental disorders which can include progressive myoclonic epilepsy (PME) and developmental epileptic ...

Researchers at Leipzig University and TU Dresden have succeeded in developing biological switches that can selectively turn ion channels on and off using light pulses. Initial applications show that ...

(Nanowerk Spotlight) Biological brains compute using ions, not electrons. Every signal between neurons depends on charged atoms passing through protein channels embedded in cell membranes, a system ...