Nancy Guthrie is among the thousands of people who go missing in the U.S. each year. But experts describe her case as "strange," with many unique details, from her age to her celebrity daughter.

When a loved one goes missing, relatives can feel guilty simply for eating, says Charlie Shunick, whose sister was kidnapped.

Mental health experts say uncertainty in missing persons cases can deepen trauma and hinder grieving.

Pennsylvania State Police are offering a $5,000 reward for information that could help lead to the solving of a missing ...